Translational and Clinical Neuroscience Laboratory
While numerous rehabilitative techniques are used to treat serious and
potentially chronic cognitive and physical deficits, there remains a lack
of available tools for effectively characterizing the temporal dynamics
and individual variability of the brain’s response to therapeutic
intervention. One area of focus in our research department is to identify
useful biomarkers (molecular, imaging, and physiological) for recovery
and treatment efficacy. In additional we want to begin to elucidate the
mechanisms of activity, pathogenesis, and recovery for a stroke, traumatic
brain injury, and spinal cord injury. Below is a list of current research
studies in this area.
Active Projects
Analysis of brain dynamics during BI rehab
TBI biomarker study: neuroendocrine dysfunction and inflammatory / neural markers
Cognitive Neural prosthetics for SCI
Role of Genetic factors in Hemorrhagic Stroke
Presence of Micro-bleeds in neurological injury
Completed Projects
Longitudinal analysis of neural and inflammatory markers in individuals with TBI
Women with the Alzheimer’s risk marker ApoE4 lose Abeta specific
CD4+ T cells 10-20 years before men
Hypothalamic Pituitary Dysfunction Following Traumatic Brain Injury
Hypothalamic-pituitary dysfunction following traumatic brain injury affects
functional improvement during acute impatient rehabilitation.
The potential use of Hormone-based therapeutics for the treatment of Alzheimer’s disease
The effect of hyperbaric oxygen therapy on functional impairments caused
by ischemic stroke
Clinical Informatics Laboratory
The majority of our research studies at Casa Colina are aimed to evaluate
the efficacy of both current and novel treatments and programs at Casa
Colina. We focus on the major diagnoses at Casa Colina to investigate
new interventions, support evidence-based clinical practices, and develop
predictive /assessment tools for the treatment of disabilities caused
by a stroke, traumatic brain injury, spinal cord injury, and other neurologic
conditions and movement disorders. Below is a list of current research
studies in this area.
Active Projects
High Risk Navigation
Cognitive decline post joint replacement surgery
Predicting Rehabilitation and Discharge Success machine learning
A new scale to assess receptive language: validation in patients with aphasia
Fall risk assessment
Rehab outcomes and prediction analysis
Textured thin liquids on improved swallow outcomes
PD Deep Brain Stimulation rehab study
Predicting driving readiness
Estim for Dysphagia
Nerve and Tendon transfer for SCI patients
Completed Projects
Swim safety and social interaction for children with Autism
Patient Navigation for Spinal Cord Injury
Patient Navigation for Traumatic Brain Injury
Senior Evaluation Program outcomes
Effects of aquatic therapy on functional mobility and strength, Fall Risk
and Self-reported disability in individuals with low back pain
The Effect of Amplification on Speech and Language Abilities In Children
with Artesia
Predicting discharge destination with admission outcome scores in stroke patients
Pinch Strength and its Relationship to Penmanship and ADLs
Use of an Algorithm for Assessment and treatment of upper extremity post stroke
Predicting and Assessing Fall Risk in an Acute Inpatient Rehabilitation Facility
Multidimensional health risk appraisal among adults aging with acquired
disabilities
Comparison of Fallers and Non-fallers at an Inpatient Rehabilitation Facility
The “Village”: A Seven-year Case study on Sustaining Healthy
Choices Among Adults with Intellectual Disabilities
Dalcroze Eurhythmics in Transitional Care Brain Injury Patients
The Effect of Liquid Modifications on Dehydration and Quality of Life
Validation of the Casa Colina Falls Assessment Scale in predicting falls
in Inpatient Rehabilitation Facilities
Technology Laboratory
Through collaborations with academic institutions and companies, we have
recently embarked on a new area of research focused on physiological monitoring
and technology. These studies investigate novel therapeutic interventions
and the use of technology for monitoring patients and augment clinical
care. Below is a list of current research studies in this area.
Active Projects
Home monitoring of gait in PD
Visual scene app for aphasia
Development of clinical tracking app
Completed Projects
Evaluation of Wearable “Smart Socks” Gait Monitoring System
for Improving Rehabilitation through Remote Gait Monitoring
LEGO interventions for Social and Language Development
Sound and Visual cues to improve gait in individuals with PD
Effects of aquatic therapy on functional mobility and strength, Fall Risk
and Self-reported disability in individuals with low back pain
For more information on current health outcomes research at Casa Colina,
please contact: Emily R. Rosario, Ph.D.
Director of Casa Colina Research Institute
909/596-7733, ext.3036
erosario@casacolina.org
