Research Participation Opportunities

This study seeks individuals with paralysis to control a computer using thought alone. Subjects with tetraplegia will learn to control the computer interface with the aid of the study team.

To be eligible, you must:

• live within one hour of Casa Colina and be able to attend 3-5 times a week for at least a year (transportation available at no cost).
• have electrodes implanted surgically and then removed after one year.

This study aims to investigate changes in electrical brain activity related to improvements in both motor and cognitive recovery following the use of taVNS in acute stroke patients.

To be eligible, you must:

• be between 18 to 80 years old.
• have first time acute cerebrovascular accident (CVA) ischemic or hemorrhagic.
• have sustained the injury within the past month.

Eligible stroke patients will try CPAP for one night. If successful, they will be assigned to a six-month study in which one group uses CPAP with support and the other does not use CPAP.

To be eligible, you must:

• be at least 18 years old.
• have experienced a recent stroke or transient ischemic attack within prior 14 days to study enrollment.

This study aims to measure the benefits of a personalized therapy program for individuals with impaired arm or hand movements, specifically focusing on improvements in motor skills and functional abilities.

To be eligible, you must:

• be at least 18 years old.
• have had an ischemic or hemorrhagic stroke within 1 week to 1 month prior to enrollment.
• have hemiparesis/weakness in arm or hand.

The purpose of this study is to utilize genetic biomarkers to accurately identify patient outcomes and develop a personalized treatment to maximize recovery following a traumatic or non-traumatic brain injury.

To be eligible, you must:

• be at least 18 years old.
• have a severe acquired brain injury.
• have no prior history of genetic, neurological, and/or psychiatric disorder.

This study aims to enhance the safety and usability of motorized mobility scooters. Your participation will help us gather data to achieve these goals and publish our findings.

To be eligible, you must:

• be at least 18 years old.
• have the ability to follow instructions in English.
• have a lower extremity impairment.

This study aims to explore how infants’ brains plan and carry out simple actions, such as reaching for a toy, using a safe and innovative functional ultrasound imaging technology. The goal is to better understand typical brain development and identify early differences that may help guide future therapies and interventions.

To be eligible, infant must:

• be 6 to 12 months old.
• be able to reach for objects or initiate reaching.
• be able to sit up independently or with minimal support.

This study aims to assess the use of brain-computer interface as an effective form of communication for patients with severe acquired brain injuries and their caregiver/family.

To be eligible, you must:

• be at least 16 years old.
• have sustained a severe acquired brain injury at least 28 days before enrolling.
• have language and motor difficulties impacting communication.